Tetrazoles: calcium oxalate crystal growth modifiers
نویسندگان
چکیده
منابع مشابه
Urinary calcium oxalate crystal growth inhibitors.
Calcium stones occur because renal tubular fluid and urine are supersaturated with respect to calcium oxalate and phosphate. The process of stone formation includes crystal nucleation, growth, aggregation, and attachment to renal epithelia. Urine contains macromolecules that modify these processes and may protect against stone formation. Attention has focused especially on inhibitors of crystal...
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Urine from mammalian kidneys is regularly supersaturated with respect to calcium oxalate monohydrate, the most common solid phase in human nephrolithiasis, and also inhibits the nucleation, growth, and aggregation of calcium oxalate crystals. Nephrolithiasis is often associated with increased supersaturation, and it is assumed that this increase overbalances the inhibition effects, causing ston...
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Modifying crystal growth processes using additives is a well established approach to solving problems in many processes. Nature also makes extensive use of crystalline inorganic structures modified by soluble and insoluble organic materials. This Highlight discusses some of the recent and interesting developments in this area, with an emphasis on the control of crystal growth rates, covering bo...
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We have determined that the organic matrix of calcium oxalate kidney stones contains a glycoprotein inhibitor of calcium oxalate crystal growth (nephrocalcin) that resembles nephrocalcin present in the urine of patients with calcium oxalate stones and differs from nephrocalcin from the urine of normal people. Pulverized calcium oxalate renal stones were extracted with 0.05M EDTA, pH 8.0; nephro...
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Urolithiasis and calcium oxalate crystal deposition diseases are still significant medical problems. In the course of nephrocalcin cDNA cloning, we have identified FKBP-12 as an inhibitory molecule of calcium oxalate crystal growth. lambdagt 11 cDNA libraries were constructed from renal carcinoma tissues and screened for nephrocalcin cDNA clones using anti-nephrocalcin antibody as a probe. Clon...
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ژورنال
عنوان ژورنال: CrystEngComm
سال: 2015
ISSN: 1466-8033
DOI: 10.1039/c4ce01717j